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Effects of Stepped Cognitive Behavioral Therapy on Child Depressive and Externalizing Symptoms in Autistic Children With Anxiety.

American journal on intellectual and developmental disabilities2025

Rast Catherine E, Guzick Andrew G, Soileau Keaton J, Smarason Orri, Berry Leandra N, Goin-Kochel Robin P, Goodman Wayne K, Schneider Sophie C, Salloum Alison, Storch Eric A

What this study means for families

Researchers studied 76 autistic children with anxiety using a step-by-step treatment approach. All children started with parent-led self-help materials, then some moved to therapist sessions. Both groups saw improvements in depression and behavior problems. Surprisingly, children who stayed with parent-led help did better than those who moved to therapist sessions, but by 3 months later, both groups were doing equally well.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Research summary

This study examined the effects of a stepped care approach for anxiety treatment on depressive and externalizing symptoms in 76 autistic youth. Participants began with parent-led bibliotherapy for 12 weeks, with 44 children stepping up to therapist-led CBT. Both groups showed reductions in depressive and externalizing symptoms at all assessment points. Interestingly, children who remained in the maintenance phase (parent-led intervention only) showed greater symptom improvements than those who stepped up to therapist-led CBT.

At 3-month follow-up, differences between groups disappeared. Parent mental health measures showed no significant changes throughout the study period.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Key findings

  • 1

    Both stepped care groups showed reductions in depressive and externalizing symptoms across all timepoints

    Confidence: moderateRelevance: Suggests stepped care approaches can address multiple symptom domains beyond the primary anxiety target
  • 2

    Children in maintenance phase showed greater symptom decreases than those who stepped up to therapist-led CBT

    Confidence: moderateRelevance: Indicates parent-led interventions may be sufficient for some children, potentially reducing treatment costs and improving accessibility
  • 3

    No between-group differences remained at 3-month follow-up

    Confidence: moderateRelevance: Suggests both approaches achieve similar long-term outcomes
  • 4

    No significant changes in parent mental health measures

    Confidence: moderateRelevance: Parent wellbeing may require targeted intervention beyond child-focused treatment

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Clinical implications

Stepped care models show promise for treating multiple symptoms in autistic youth with anxiety. Parent-led interventions may be adequate for many families, supporting more accessible treatment delivery. Clinicians should consider that not all children require intensive therapist-led interventions to achieve meaningful improvements in comorbid symptoms.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Limitations

Sample size appears modest for stepped care design. Study type is unknown, limiting interpretation of methodology quality. No control group comparison reported. Unclear selection criteria for stepping up to therapist-led care, which could introduce bias in comparing intervention intensities.

Summary by AutismInsights from published abstract. This is not a substitute for reading the original paper.

Original abstract

Despite the strong evidence basis for the treatment of anxiety in autistic youth, accessibility remains a significant challenge. Stepped care addresses this gap, although there is limited research into its broad effects in autistic youth with anxiety. In this project, 76 autistic youth with anxiety entered parent-led-bibliotherapy for 12 weeks; 44 stepped up to receive therapist-led cognitive behavioral therapy (CBT). Those who did not step up entered a maintenance phase.

Youth were assessed for externalizing and depressive symptoms at mid-treatment, post-treatment, and 3 months after treatment (3MFU). Focal symptoms decreased across groups at all timepoints; those who entered maintenance experienced greater decreases. At 3MFU there were no differences between groups. Parents were assessed for depression, anxiety, and stress at the same timepoints; no significant changes were observed.

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Evidence Grade

Emerging

limited

Grade assigned by AutismInsights based on study type and published abstract.

Study Details

Journal
American journal on intellectual and developmental disabilities
Year
2025
PMID
40288774
DOI
10.1352/1944-7558-130.3.228

MeSH Terms

HumansCognitive Behavioral TherapyFemaleMaleChildDepressionAnxietyAdolescentAutistic DisorderAutism Spectrum Disorder